In the 1940′s the archetype of The Mad Scientist was prevalent in all media from movie serials to comic books. Most people didn’t think such characters actually existed, but they instilled fear in the audience who were afraid of science after the advent of the atomic bomb.
Little did they know that over in communist Russia Mad Scientists were hard at work on a freaky Frankenstein-lite experiment. By hooking the severed head of a dog up to a blood pump the head re-animates and reacts to stimuli.
Uber-creepy, but it does suggest that the Jar Heads featured in Futurama might just exist some day.